By using biochemical and molecular & cellular biological techniques, we perform fundamental researches on roles of chromatin modifications in the control mechanism of life phenomena to happen at a cell level, e.g., DNA replication, transcription, DNA damage & repair, genome instability, and cell differentiation in animal cells. On the other hand, we aim at applying knowledge provided by these to the field over many divergences of bioscience and its related research area. In addition, we also devote to a study on action and utilization of various functional ingredients (including vitamins) derived from food.